Reviewing a Function-First Approach to Designing Multispecifics & T-Cell Engagers
9:00 am - Wednesday 11th November 2026
- Translate therapeutic intent and disease biology into fit-for-purpose multispecific architectures, rather than starting with a preferred molecular format
- Examine how target combination, geometry, affinity, valency, and immune-cell engagement interact to determine coordinated function and therapeutic performance
- Explore how computational, structural, and experimental workflows can be integrated to reduce design space, accelerate optimization, and improve developability and translational potential
